Department of Respiratory Failure

Our purpose is the clinical research of respiratory infectious diseases, particularly tuberculosis, nontuberculous mycobacterial (NTM) diseass and fungal diseases. Kinki-chuo Chest Medical Center is designated as one of the two highly-specialized hospital for tuberculosis in Japan. The hospital has a ward for tuberculosis patients equipped with air conditioning for treating multidrug-resistant tuberculosis (MDRTB) patients. We have a great deal of experience in treating intractable mycobacterial diseases including MDRTB and NTM diseases. We performed various bacteriological analysis including molecular typing for mycobacteria such as VNTR and PFGE, molecular identification for mycobacterial species, drug sensitivity testing. We make use of the results of these analysis for better treatment of the diseases.

* Physiological aspects of interstitial lung diseases (ILDs) and autoimmune pulmonary alveolar proteinosis (APAP)
* Predictive factors and prognostic factors of acute exacerbation in IIPs
* Single Arm Open Labeled Multicenter Trial for Safety and Efficacy of recombinant human soluble Thrombomodulin for Acute Exacerbation of Idiopathic Interstitial Pneumonias (SETUP Trial)
* Lower lobe predominance sarcoidosis
* Standardization of whole lung lavage for APAP
* Importance of emphysema complicated with Interstitial pneumonia
* Gene polymorphism in ILDs and APAP
* Rehabilitation of APAP before and after whole lung lavage
* Compliance of continuous positive airway pressure in sleep apnea syndrome
* Registration of COPD